Ingredients
In collaboration with Quintis
With cannabidiol (CBD oil) recently banned from use in cosmetics in China and other markets that restrict the use of the oil, such as the UK and Australia, cosmetic formulators are being encouraged to consider the Indian sandalwood oil as an effective alternative to CBD oil after a new scientific review revealing Indian sandalwood oil has more confirmed benefits.
Indian sandalwood oil (Santalum album) is considered the most luxurious of all sandalwood oils and is obtained by steam distillation of the aromatic heartwood of the tree. It has been used for centuries in cosmetics, such as Ayurvedic skin care, topical treatments based on the principles of a 5,000-year-old Indian health system, with sandalwood appearing in the Charaka Samhita, an Ayurvedic Sanskrit text. , more than 2,000 years ago.
Today, Indian sandalwood oil is fast becoming a new trend ingredient in a myriad of beauty and personal care applications. Extensive sustainable supply is now available in Australia through companies such as Quintis Sandalwood, with more research proving its effectiveness.
To show the power of Indian sandalwood oil as an alternative to CBD oil in cosmetics, Quintis Sandalwood has recently conducted a review of existing scientific studies to evaluate the benefits of each.
The findings revealed that sandalwood oil from India has more scientifically proven advantages compared to CBD oil, making it a good substitute in cosmetic applications, especially in skin care.
Dr. Dhanushka Hettiarachchi, Ph.D., product director at Quintis Sandalwood, said Indian sandalwood oil is a real game changer for cosmetics.
“While CBD oil appears to be a popular choice with some scientific literature available, most current claims about CBD skin activity are based on anecdotal evidence; more research is needed to truly prove its efficiency and power.
“Sandalwood oil from India is an excellent natural versatile ingredient for the care of cosmetics and an alternative to CBD oil as it is an effective protective and anti-aging active ingredient, and has scientifically demonstrated bioactivity and dermal benefits for the skin, including helping with evening skin tone and wound healing, ”says Dr. Hettiarachchi.
“Indian sandalwood oil can be included in products like face washes, moisturizers and serums in different concentrations for a deep penetrating action and body care products like natural deodorant. Other products that can be used Sandalwood are water-based facial sprays, washes and hydrogels that can be prepared by emulsifying the oil for its aroma and antioxidant benefits for the skin ”.
The scientific review found that sandalwood oil from India is similar or more effective than CBD oil in the following five key benefits and claims, which are important for skin care formulations:
- Wound healing Both CBD oil and Indian sandalwood oil act on the proliferation of keratinocytes to facilitate wound healing. Both do this by stimulating the calcium channels of keratinocytes, but sandalwood oil from India acts specifically on the OR2AT4 receptor.[4], while CBD oil acts specifically on the CBD receptor CB-1[6].
- Skin illumination – Studies have shown that sandalwood oil from India inhibits the enzyme tyrosinase, the key enzyme in the production of melanin, responsible for uneven skin tone, dark spots and pigmentation.[5]. To date, there is no research to suggest that CBD may inhibit the enzyme tyrosinase or reduce skin melanin production, with CBD’s lightening claims derived from its antioxidant properties.
- Antioxidant – According to a study recently published in the Cosmetics Journal, commissioned by Quintis Sandalwood, Indian sandalwood oil is a powerful antioxidant that works on keratinocytes to protect the skin from the reactive oxygen species (ROS) generated by exposure to environmental stressors such as blue light. and pollution. ROS are free radicals that cause damage to cell structure, break down collagen, reduce elasticity and cause a uniform skin tone. [1]. CBD oil has antioxidant properties similar to ISO, working on keratinocytes to protect the skin from reactive oxygen species (ROS) [6,7].
- Anti-inflammatory – Sandalwood oil from India is widely known for its ability to inhibit the production of cytokines / chemokines (IL, TNF-a) and prostaglandins, which cause inflammation in the skin, which eventually causes pigmentation and collagen degradation. It also regulates the enzyme 11βHSD1 to convert covert inflammatory cortisone into inactive cortisol [2,3,4]. CBD stimulates CB-2 receptors in the skin to reduce cytokine chemokine, but the mechanism remains ambiguous. [6,7].
- Anti-aging – Indian sandalwood oil inhibits the enzyme MMP1 generated in the skin when a person is exposed to certain internal (lifestyle) and environmental stressors. The enzyme MMP1 is responsible for breaking down collagen[1]. A reduction in collagen can cause an increase in fine lines / wrinkles and reduce the elasticity and thickness of the skin. To date, there is no research to suggest that CBD may inhibit the enzyme MMP1, as the anti-aging claims of CBD are derived from its antioxidant properties.[6].
“Our sandalwood oil from India has more than 20 international certifications, including approval in the Chinese Inventory of Existing Cosmetic Ingredients, listed as a safe ingredient in the U.S. Food and Drug Administration (FDA ) and meets the standards of the British Pharmacopoeia. there is a great opportunity for this precious medicinal ingredient to be considered a high quality substitute for CBD oil.
From its benefits for the skin, such as antithyrosinase and antimicrobial activity, to its soothing properties, sandalwood oil from India is the perfect ingredient for holistic cosmetic applications, ”says Dr. Hettiarachchi . Samples of sandalwood oil from India can be requested through the Quintis Sandalwood website.
References:
1. Francois-Newton, V., et al. (2021). “Antioxidant and anti-aging potential of Indian sandalwood oil against in vitro and ex vivo environmental stressors.” Cosmetics 8 (2): 53.
2. Sharma, M., et al. (2018). “East India Sandalwood Oil is a Phosphodiesterase Inhibitor: A New Therapeutic Option in the Treatment of Inflammatory Skin Diseases.” Frontiers in Pharmacology 9: 200.
3. Sharma, M., et al. (2014). “Suppression of lipopolysaccharide-stimulated cytokine / chemokine production in skin cells by purified sandalwood and α-santalol and β-santalol oils.” Phytotherapy Research 28 (6): 925-932.
4. Moy, RL and C. Levenson (2017). “Sandalwood Album Oil as a Botanical Therapist in Dermatology.” The Journal of Clinical and Aesthetic Dermatology 10 (10): 34.
5. Misra, BB and S. Dey (2013). “TLC-bioautographic evaluation of the anti-tyrosinase and anti-cholinesterase potential in vitro of sandalwood oil”. Natural Product Communications 8 (2): 1934578X1300800231.
6. Baswan, SM, Klosner, AE, Glynn, K., Rajgopal, A., Malik, K., Yim, S. and Stern, N. (2020). “Therapeutic potential of cannabidiol (CBD) for skin health and disorders. Clinical, Cosmetic, and Research Dermatology, 13, 927.
7. Liu, C., Li, H., Xu, F., Jiang, X., Ma, H. and Seeram, NP (2021). “Cannabidiol protects keratinocytes in human skin from hydrogen peroxide-induced oxidative stress by modulating the Caspase-1-IL-1β axis.” Journal of Natural Products, 84 (5), 1563.
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