Could CBD Use Help Slow the Growth of Cancerous Tumors?


Big C is a serious disease that affects the world’s major populations.

Olena Ruban | Getty Images

According to the World Health Organization (WHO), cancer killed about 10 million people worldwide in 2020 alone. It is still the leading cause of death in the world, affecting more than just families and societies in general , but it also has a huge effect on the economy.

While early detection is always the best scenario for treatment and improved prognosis, it is not always possible. Treatment for cancers and tumors includes one or a combination of methods such as chemotherapy, radiation therapy, or surgery. However, if the tumors are of a higher grade, treatment may require surgery as well as radiation therapy and chemotherapy.

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How Cannabis Helps With Cancer

A new study from the University of Augusta, focusing on glioblastoma, one of the deadliest and fastest-growing forms of brain tumors, reveals that cannabidiol (CBD) is a beneficial form of treatment. The prognosis of glioblastoma is a 15-month survival rate after diagnosis, based on data from the Glioblastoma Foundation. Despite new cancer research over the past 15 years, survival has only increased in 2 months, says Dr. Martin Rutkowski, a Georgian medical doctor at the AU Neurosurgeon, and one of the study’s researchers.

“We’re pretty desperate for better therapies,” he tells Augusta Chronicle.

Cannabidiol has great potential for tumor therapy, says Dr. Babak Baban, a research associate dean at the Georgia Dental College. It is considered relatively safe and has been shown to help regulate the immune system effectively. Baban explains that glioblastomas create a microenvironment that is “one of the most complex for tumors.”

Tumors grow creating new blood vessels, a process known as angiogenesis. “Through angiogenesis, it can spread, it can survive,” he says. Therefore, glioblastoma “is the most aggressive of the central nervous system.”

The researchers used subject mice that were made to produce tumors internally and were then administered with inhaled CBD. After that, the tumors were significantly reduced in size compared to mice that did not receive any CBD. In addition, they found that CBD appeared to obstruct at least 3 components needed for angiogenesis to occur.

Other than that, glioblastomas are difficult to treat because they bypass the immune system through immune checkpoints. Rutkowski clarifies this by comparing it to a protective barrier that forms around the tumor. “They’re great for protecting themselves, so we need ways to drop the shield and make the immune system more effective at finding them,” he says.

“I’m skeptical when it comes to CBD to deal with depression or anxiety, financial anxiety or marital problems,” she says. “That’s probably not true. But now that we have a basic science that supports this therapy, I think it’s really exciting.”

“Overall, our new findings support the potential therapeutic role of inhaled CBD as a complement to effective, relatively safe, and easy-to-administer treatment for GBM with significant impacts on cellular and molecular signaling of TME (tumor microenvironment). ) which guarantees more research “, conclude the authors.

In October 2021, doctors in the UK published an article documenting an 80-year-old woman who was diagnosed with lung cancer. The case, published in BMJ Case Reports, details his medical history which included high blood pressure, chronic obstructive pulmonary disease and osteoarthritis.

The woman admitted to smoking more than one pack of cigarettes a week, both before and after her diagnosis. In June and July 2018, doctors tested her with a PET scan, an MRI, a CT scan, and a biopsy. He was diagnosed with stage IIB non-small cell lung cancer (NSCLC). In September 2019, the CT scan of the chest was repeated, showing 2 new nodules in the right upper lobe and left apex. She refused surgery to remove the lobe because of the risks, and also declined radiofrequency ablation due to the side effects her late husband suffered from radiation therapy.

At this time, he admitted to having started treatment with CBD oil with 0.5 ML 3 times a day orally, then twice a day, after being diagnosed. The CBD oil supplier advised him not to take CBD oil with a hot drink or food to avoid the stone feeling, and also reported a reduction in appetite with CBD oil. Despite this, she made no changes to her lifestyle or diet, and even continued to smoke a pack of cigarettes a week.

“We definitely did not expect to see such a dramatic tumor regression without conventional cancer treatments and without other health or lifestyle changes … Multiple studies to date in animal models have shown conflicting results, with some cases reducing cancer cells and others finding accelerated growth of cancer cells, “said lead author Dr. Kah Ling Liew.

Dr. Jack Jacoub, medical director of the MemorialCare Cancer Institute at Orange Coast Medical Center and a medical oncologist, told Medical News Today: Recommended treatment option for cancer patients. .

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Use cannabis with other cancer therapies

Although more research is needed in this area, there are already several promising studies that indicate that CBD is effective, especially when used in addition to other conventional cancer therapies.

In addition, radiation and chemotherapy are known for their side effects, often bad enough to discourage patients from continuing therapy and affect survival rates. The most common side effects are loss of appetite and nausea, which lead to weight loss.

Many studies show the effectiveness of cannabis in mitigating these side effects; CBD can suppress the anxiety associated with having cancer or going to chemotherapy and radiation treatments, while THC can improve appetite.

If you want to consider using CBD along with other therapies to beat the tumors, the best advice is to always do it under the supervision of your doctor.

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